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Circulation Preclinical Study

Red/near Infrared Light Stimulates Release Of An Endothelium-Dependent Vasodilator And Rescues Vascular Dysfunction In A Diabetes Model.

Source publication · 2017 · Keszler, A., Lindemer, B., Weihrauch, D., et al.

Research Summary

This laboratory study investigated whether 670 nm light could relax blood vessels through nitric-oxide-related signalling. It examined a possible mechanism rather than testing a treatment in patients.

Who Or What Was Studied?

Experiments used isolated mouse blood vessels, including a diabetic mouse model, and cultured human microvascular endothelial cells. Human cells in culture are not human trial participants.

What Did The Research Show?

  • Light increased vessel dilation, including in vessels from diabetic mice. Removing the vessel lining or scavenging nitric oxide abolished the response.
  • The findings suggest that the vessel lining releases nitric-oxide-carrying substances in response to light.

Limitations And Interpretation

  • These experiments do not demonstrate improved circulation, symptom relief or healing in people with diabetes.
  • An isolated-vessel response cannot establish an effective or safe whole-body treatment protocol.

Based on the PubMed abstract. A 2019 correction is indexed; its full text has not been assessed, so this summary requires checking against that correction before publication.

Source: PubMed abstract and correction notice listing ↗

Published correction (2019) ↗